The volume of uterine fluid in 'implanting' and 'delayed implanting' mice

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On the orientation of the implanting blastocyst.

In viviparous mammals the implanting blastocyst is positioned according to a number of parameters which are species specific. First, in polytocous animals the blastocysts become spaced out along the length of the uterus, secondly they take up a particular relationship to the circumference of the endometrium, and lastly the embryonic pole always assumes a constant orientation to the mesometrial-...

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Insights from imaging the implanting embryo and the uterine environment in three dimensions.

Although much is known about the embryo during implantation, the architecture of the uterine environment in which the early embryo develops is not well understood. We employed confocal imaging in combination with 3D analysis to identify and quantify dynamic changes to the luminal structure of murine uterus in preparation for implantation. When applied to mouse mutants with known implantation de...

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Implanting outside the guidelines: a case study.

An 81-year-old female was referred for cochlear implantation due to difficulty communicating in her daily activities despite the use of appropriate amplification. The poorer ear was unable to tolerate amplification for the past 15 years. The open-set sentence-recognition test score in quiet in her "good" ear was 85 percent correct, indicating that the patient was not a traditional cochlear impl...

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Progesterone and implanting blastocysts regulate Muc1 expression in rabbit uterine epithelium.

Mammalian uteri are unreceptive to blastocyst implantation except during a relatively brief period. The transmembrane, cell surface mucin, Muc1, is present on epithelial cells of nonreceptive uteri in various species and has been demonstrated to have antiadhesive properties. These activities of Muc1 may prevent interaction of the embryonic trophoblast cells with the uterine epithelium. A previo...

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MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos.

STUDY QUESTION Does Let-7a have a functional role in modulating dicer expression to activate dormant mouse blastocysts for implantation? SUMMARY ANSWER Let-7a post-transcriptionally regulates dicer expression altering microRNA expression to affect the implantation competency of the activated blastocysts. WHAT IS KNOWN ALREADY The Let-7a microRNA is up-regulated during blastocyst dormancy an...

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ژورنال

عنوان ژورنال: Reproduction

سال: 1981

ISSN: 1470-1626,1741-7899

DOI: 10.1530/jrf.0.0620105